Recombinant Human PREB Protein, Myc/DDK-tagged, C13 and N15-labeled PREB-520H

Recombinant Human PREB Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	PREB-520H
Product Overview :	PREB MS Standard C13 and N15-labeled recombinant protein (NP_037520) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	45.5 kDa
AA Sequence :	MGRRRAPELY RAPFPLYALQ VDPSTGLLIA AGGGGAAKTG IKNGVHFLQL ELINGRLSAS LLHSHDTETR ATMNLALAGD ILAAGQDAHC QLLRFQAHQQ QGNKAEKAGS KEQGPRQRKG AAPAEKKCGA ETQHEGLELR VENLQAVQTD FSSDPLQKVV CFNHDNTLLA TGGTDGYVRV WKVPSLEKVL EFKAHEGEIE DLALGPDGKL VTVGRDLKAS VWQKDQLVTQ LHWQENGPTF SSTPYRYQAC RFGQVPDQPA GLRLFTVQIP HKRLRQPPPC YLTAWDGSNF LPLRTKSCGH EVVSCLDVSE SGTFLGLGTV TGSVAIYIAF SLQCLYYVRE AHGIVVTDVA FLPEKGRGPE LLGSHETALF SVAVDSRCQL HLLPSRRSVP VWLLLLLCVG LIIVTILLLQ SAFPGFLTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	PREB prolactin regulatory element binding [ Homo sapiens (human) ]
Official Symbol :	PREB
Synonyms :	PREB; prolactin regulatory element binding; prolactin regulatory element-binding protein; SEC12; prolactin regulatory binding-element protein; mammalian guanine nucleotide exchange factor mSec12; MGC3467;
Gene ID :	10113
mRNA Refseq :	NM_013388
Protein Refseq :	NP_037520
MIM :	606395
UniProt ID :	Q9HCU5