Recombinant Human Prefoldin Subunit 2, His-tagged

• Cat.No.: PFDN2-2857H
• Product Overview: Recombinant human PFDN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 18.8kDa (174aa) confirmed by MALDI-TOF.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PFDN2 (Prefoldin subunit 2) is a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. This protein binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. And binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MAENSGRAGK SSGSGAGKGA VSAEQVIAGF NRLRQEQRGL ASKAAELEME LNEHSLVIDT LKEVDETRKC YRMVGGVLVE RTVKEVLPAL ENNKEQIQKI IETLTQQLQA KGKELNEFRE KHNIRLMGED EKPAAKENSE GAGAKASSAG VLVS
• Purity: > 90% by SDS – PAGE.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 50mM NaCl.
• Concentration: 0.5mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PFDN2 prefoldin subunit 2 [ Homo sapiens ]
• Synonyms: PFDN2; prefoldin subunit 2; PFD2; prefoldin 2
• Gene ID: 5202
• mRNA Refseq: NM_012394
• Protein Refseq: NP_036526
• MIM: 611099
• UniProt ID: Q9UHV9
• Chromosome Location: 1q23.3
• Function: protein binding; unfolded protein binding