"PRKAB2" Related Products

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Recombinant Human PRKAB2 protein, His-tagged

Cat.No.: PRKAB2-237H
Product Overview: Recombinant Human PRKAB2 fused with His tag at N-terminal was expressed in E.coli.
Description: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Source: E. coli
Species: Human
Tag : His
Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Mass: 30.1 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit [ Homo sapiens ]
Official Symbol: PRKAB2
Synonyms: PRKAB2; protein kinase, AMP-activated, beta 2 non-catalytic subunit; 5-AMP-activated protein kinase subunit beta-2; AMPK beta 2; AMPK beta-2 chain; AMPK subunit beta-2; 5-AMP-activated protein kinase, beta-2 subunit; MGC61468;
Gene ID: 5565
mRNA Refseq: NM_005399
Protein Refseq: NP_005390
MIM: 602741
UniProt ID: O43741

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