Recombinant Human PRKACB Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PRKACB-2407H
• Product Overview: PRKACB MS Standard C13 and N15-labeled recombinant protein (NP_002722) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 40.6 kDa
• AA Sequence: MGNAATAKKGSEVESVKEFLAKAKE DFLKKWENPTQNNAGLEDFERKKTL GTGSFGRVMLVKHKATEQYYAMKIL DKQKVVKLKQIEHTLNEKRILQAVN FPFLVRLEYAFKDNSNLYMVMEYVP GGEMFSHLRRIGRFSEPHARFYAAQ IVLTFEYLNSLDIIYRDLKPENLLI DHQGYIQVTDFGFAKRVKGRTWTLC GTPEYLAPEIILSKGYNKAVDWWAL GVLIYEMAAGYPPFFADQPIQIYEK IVSGKVRFPSNFSSDLKDLLRNLLQ VDLTKRFGNLKNGVSDIKTHKWFAT TDWIAIYQRKVEAPFIPKFRGSGDT SNFDDYEEEDIRVSITEKCAKEFGE FTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PRKACB protein kinase cAMP-activated catalytic subunit beta [ Homo sapiens (human) ]
• Official Symbol: PRKACB
• Synonyms: PRKACB; protein kinase, cAMP-dependent, catalytic, beta; cAMP-dependent protein kinase catalytic subunit beta; PKACb; PKA C-beta; protein kinase A catalytic subunit beta; cAMP-dependent protein kinase catalytic beta subunit isoform 4ab; PKACB; MGC9320; MGC41879; DKFZp781I2452
• Gene ID: 5567
• mRNA Refseq: NM_002731
• Protein Refseq: NP_002722
• MIM: 176892
• UniProt ID: P22694