Recombinant Human PRKAG2 protein, His-tagged

• Cat.No.: PRKAG2-234H
• Product Overview: Recombinant Human PRKAG2, transcript variant c, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 58.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit [ Homo sapiens ]
• Official Symbol: PRKAG2
• Synonyms: PRKAG2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; 5-AMP-activated protein kinase subunit gamma-2; AAKG; AAKG2; AMPK gamma2; CMH6; H91620p; WPWS; AMPK subunit gamma-2
• Gene ID: 51422
• mRNA Refseq: NM_001040633
• Protein Refseq: NP_001035723
• MIM: 602743
• UniProt ID: Q9UGJ0