| Description : |
The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
77.5 kDa |
| AA Sequence : |
MAPFLRIAFNSYELGSLQAEDEANQ PFCAVKMKEALSTERGKTLVQKKPT MYPEWKSTFDAHIYEGRVIQIVLMR AAEEPVSEVTVGVSVLAERCKKNNG KAEFWLDLQPQAKVLMSVQYFLEDV DCKQSMRSEDEAKFPTMNRRGAIKQ AKIHYIKNHEFIATFFGQPTFCSVC KDFVWGLNKQGYKCRQCNAAIHKKC IDKIIGRCTGTAANSRDTIFQKERF NIDMPHRFKVHNYMSPTFCDHCGSL LWGLVKQGLKCEDCGMNVHHKCREK VANLCGINQKLLAEALNQVTQRASR RSDSASSEPVGIYQGFEKKTGVAGE DMQDNSGTYGKIWEGSSKCNINNFI FHKVLGKGSFGKVLLGELKGRGEYF AIKALKKDVVLIDDDVECTMVEKRV LTLAAENPFLTHLICTFQTKDHLFF VMEFLNGGDLMYHIQDKGRFELYRA TFYAAEIMCGLQFLHSKGIIYRDLK LDNVLLDRDGHIKIADFGMCKENIF GESRASTFCGTPDYIAPEILQGLKY TFSVDWWSFGVLLYEMLIGQSPFHG DDEDELFESIRVDTPHYPRWITKES KDILEKLFEREPTKRLGVTGNIKIH PFFKTINWTLLEKRRLEPPFRPKVK SPRDYSNFDQEFLNEKARLSYSDKN LIDSMDQSAFAGFSFVNPKFEHLLE DTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
