- Human(5)
- Mouse(1)
- Rhesus Macaque(1)
- Zebrafish(1)
Recombinant Human PRMT2 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | PRMT2-5188H |
| Product Overview : | PRMT2 MS Standard C13 and N15-labeled recombinant protein (NP_001526) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 48.9 kDa |
| AA Sequence : | MATSGDCPRS ESQGEEPAEC SEAGLLQEGV QPEEFVAIAD YAATDETQLS FLRGEKILIL RQTTADWWWG ERAGCCGYIP ANHVGKHVDE YDPEDTWQDE EYFGSYGTLK LHLEMLADQP RTTKYHSVIL QNKESLTDKV ILDVGCGTGI ISLFCAHYAR PRAVYAVEAS EMAQHTGQLV LQNGFADIIT VYQQKVEDVV LPEKVDVLVS EWMGTCLLFE FMIESILYAR DAWLKEDGVI WPTMAALHLV PCSADKDYRS KVLFWDNAYE FNLSALKSLA VKEFFSKPKY NHILKPEDCL SEPCTILQLD MRTVQISDLE TLRGELRFDI RKAGTLHGFT AWFSVHFQSL QEGQPPQVLS TGPFHPTTHW KQTLFMMDDP VPVHTGDVVT GSVVLQRNPV WRRHMSVALS WAVTSRQDPT SQKVGEKVFP IWRSGPTRTR RLEQKLISEE DLAANDILDY KDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | PRMT2 protein arginine methyltransferase 2 [ Homo sapiens (human) ] |
| Official Symbol : | PRMT2 |
| Synonyms : | PRMT2; protein arginine methyltransferase 2; HMT1 (hnRNP methyltransferase, S. cerevisiae) like 1, HMT1 hnRNP methyltransferase like 1 (S. cerevisiae), HRMT1L1; protein arginine N-methyltransferase 2; MGC111373; PRMT2 beta; PRMT2 alpha; PRMT2 gamma; HMT1 hnRNP methyltransferase-like 1; histone-arginine N-methyltransferase PRMT2; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1; HRMT1L1; |
| Gene ID : | 3275 |
| mRNA Refseq : | NM_001535 |
| Protein Refseq : | NP_001526 |
| MIM : | 601961 |
| UniProt ID : | P55345 |
◆ Recombinant Protein
| Prmt2-1170M | Recombinant Mouse Prmt2 Protein, MYC/DDK-tagged | +Inquiry |
| PRMT2-5034Z | Recombinant Zebrafish PRMT2 | +Inquiry |
| PRMT2-31115TH | Recombinant Human PRMT2, His-tagged | +Inquiry |
| PRMT2-12H | Recombinant Human PRMT2 protein, GST-tagged | +Inquiry |
| PRMT2-125H | Recombinant Human PRMT2 protein, GST-tagged | +Inquiry |
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◆ Lysates
| PRMT2-2839HCL | Recombinant Human PRMT2 293 Cell Lysate | +Inquiry |
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