Recombinant Human PRMT5&MEP50 protein, Flag/His-tagged

• Cat.No.: PRMT5&MEP50-315H
• Product Overview: Recombinant Human PRMT5 2-637(C-term.) and MEP50 2-342 (C-term.) fused with N-terminal Flag (PRMT5), N-terminal His (MEP50) was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: 2-637;2-342 a.a.
• Form: Solution of purified recombinant protein in 50 mM Tris/HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM TCEP, 20% (v/v) glycerol.
• Molecular Mass: 73.7/39.90 kDa
• Storage: Store at -80 centigrade, aliquot and snap-freeze after first use.

Gene Information

• Gene Name: PRMT5 protein arginine methyltransferase 5 [ Homo sapiens ]
• Official Symbol: PRMT5
• Synonyms: PRMT5; protein arginine methyltransferase 5; HRMT1L5, SKB1, skb1 (S. pombe) homolog , SKB1 homolog (S. pombe); protein arginine N-methyltransferase 5; SKB1Hs; SKB1 homolog; jak-binding protein 1; 72 kDa ICln-binding protein; HMT1 hnRNP methyltransferase-like 5; shk1 kinase-binding protein 1 homolog; histone-arginine N-methyltransferase PRMT5; JBP1; SKB1; IBP72; HRMT1L5
• Gene ID: 10419
• mRNA Refseq: NM_006109
• Protein Refseq: NP_006100
• MIM: 604045
• UniProt ID: O14744
• Chromosome Location: 14q11.2
• Pathway: E2F transcription factor network, organism-specific biosystem; Gene expression, organism-specific biosystem; Metabolism of non-coding RNA, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem; p53 pathway, organism-specific biosystem;
• Function: histone-arginine N-methyltransferase activity; methyltransferase activity; protein binding; protein-arginine omega-N symmetric methyltransferase activity; ribonucleoprotein complex binding; transferase activity