Recombinant Human PRMT5&MEP50 protein, Flag/His-tagged
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Cat.No. :
PRMT5&MEP50-315H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant Human PRMT5 2-637(C-term.) and MEP50 2-342 (C-term.) fused with N-terminal Flag (PRMT5), N-terminal His (MEP50) was expressed in HEK293.
Source :
Insect cell
Species :
Human
Tag :
Flag/His
Form :
Solution of purified recombinant protein in 50 mM Tris/HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM TCEP, 20% (v/v) glycerol.
Molecular Mass :
73.7/39.90 kDa
Storage :
Store at -80 centigrade, aliquot and snap-freeze after first use.
Gene Name :
PRMT5 protein arginine methyltransferase 5 [ Homo sapiens ]
Official Symbol :
PRMT5
Synonyms :
PRMT5; protein arginine methyltransferase 5; HRMT1L5, SKB1, skb1 (S. pombe) homolog , SKB1 homolog (S. pombe); protein arginine N-methyltransferase 5; SKB1Hs; SKB1 homolog; jak-binding protein 1; 72 kDa ICln-binding protein; HMT1 hnRNP methyltransferase-like 5; shk1 kinase-binding protein 1 homolog; histone-arginine N-methyltransferase PRMT5; JBP1; SKB1; IBP72; HRMT1L5;
Gene ID :
10419
mRNA Refseq :
NM_006109
Protein Refseq :
NP_006100
MIM :
604045
UniProt ID :
O14744
Chromosome Location :
14q11.2
Pathway :
E2F transcription factor network, organism-specific biosystem; Gene expression, organism-specific biosystem; Metabolism of non-coding RNA, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem; p53 pathway, organism-specific biosystem;
Function :
histone-arginine N-methyltransferase activity; methyltransferase activity; protein binding; protein-arginine omega-N symmetric methyltransferase activity; ribonucleoprotein complex binding; transferase activity;
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.