Recombinant Human PRPF6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PRPF6-3647H
• Product Overview: PRPF6 MS Standard C13 and N15-labeled recombinant protein (NP_036601) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 106.9 kDa
• AA Sequence: MNKKKKPFLGMPAPLGYVPGLGRGA TGFTTRSDIGPARDANDPVDDRHAP PGKRTVGDQMKKNQAADDDDEDLND TNYDEFNGYAGSLFSSGPYEKDDEE ADAIYAALDKRMDERRKERREQREK EEIEKYRMERPKIQQQFSDLKRKLA EVTEEEWLSIPEVGDARNKRQRNPR YEKLTPVPDSFFAKHLQTGENHTSV DPRQTQFGGLNTPYPGGLNTPYPGG MTPGLMTPGTGELDMRKIGQARNTL MDMRLSQVSDSVSGQTVVDPKGYLT DLNSMIPTHGGDINDIKKARLLLKS VRETNPHHPPAWIASARLEEVTGKL QVARNLIMKGTEMCPKSEDVWLEAA RLQPGDTAKAVVAQAVRHLPQSVRI YIRAAELETDIRAKKRVLRKALEHV PNSVRLWKAAVELEEPEDARIMLSR AVECCPTSVELWLALARLETYENAR KVLNKARENIPTDRHIWITAAKLEE ANGNTQMVEKIIDRAITSLRANGVE INREQWIQDAEECDRAGSVATCQAV MRAVIGIGIEEEDRKHTWMEDADSC VAHNALECARAIYAYALQVFPSKKS VWLRAAYFEKNHGTRESLEALLQRA VAHCPKAEVLWLMGAKSKWLAGDVP AARSILALAFQANPNSEEIWLAAVK LESENDEYERARRLLAKARSSAPTA RVFMKSVKLEWVQDNIRAAQDLCEE ALRHYEDFPKLWMMKGQIEEQKEMM EKAREAYNQGLKKCPHSTPLWLLLS RLEEKIGQLTRARAILEKSRLKNPK NPGLWLESVRLEYRAGLKNIANTLM AKALQECPNSGILWSEAIFLEARPQ RRTKSVDALKKCEHDPHVLLAVAKL FWSQRKITKAREWFHRTVKIDSDLG DAWAFFYKFELQHGTEEQQEEVRKR CESAEPRHGELWCAVSKDIANWQKK IGDILRLVAGRIKNTFTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PRPF6 pre-mRNA processing factor 6 [ Homo sapiens (human) ]
• Official Symbol: PRPF6
• Synonyms: PRPF6; PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae); C20orf14, chromosome 20 open reading frame 14, PRP6 pre mRNA processing factor 6 homolog (yeast); pre-mRNA-processing factor 6; ANT 1; bB152O15.1; Prp6; TOM; U5 102K; PRP6 homolog; U5-102 kDa protein; U5 snRNP-associated 102 kDa protein; androgen receptor N-terminal domain transactivating protein-1; androgen receptor N-terminal domain-transactivating protein 1; putative mitochondrial outer membrane protein import receptor; p102 U5 small nuclear ribonucleoprotein particle-binding protein; ANT1; ANT-1; hPrp6; U5-102K; C20orf14
• Gene ID: 24148
• mRNA Refseq: NM_012469
• Protein Refseq: NP_036601
• MIM: 613979
• UniProt ID: O94906