Recombinant Human PRTN3 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: PRTN3-252H
• Product Overview: PRTN3 MS Standard C13 and N15-labeled recombinant protein (NP_002768) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. [UniProtKB/Swiss-Prot Function]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 27.6 kDa
• AA Sequence: MAHRPPSPALASVLLALLLSGAARA AEIVGGHEAQPHSRPYMASLQMRGN PGSHFCGGTLIHPSFVLTAAHCLRD IPQRLVNVVLGAHNVRTQEPTQQHF SVAQVFLNNYDAENKLNDILLIQLS SPANLSASVATVQLPQQDQPVPHGT QCLAMGWGRVGAHDPPAQVLQELNV TVVTFFCRPHNICTFVPRRKAGICF GDSGGPLICDGIIQGIDSFVIWGCA TRLFPDFFTRVALYVDWIRSTLRRV EAKGRPTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PRTN3 proteinase 3 [ Homo sapiens (human) ]
• Official Symbol: PRTN3
• Synonyms: PRTN3; proteinase 3; myeloblastin; ACPA; AGP7; C ANCA; MBT; P29; PR 3; serine proteinase; neutrophil; Wegener granulomatosis autoantigen; NP-4; C-ANCA antigen; wegener autoantigen; leukocyte proteinase 3; neutrophil proteinase 4; azurophil granule protein 7; serine proteinase, neutrophil; MBN; NP4; PR3; PR-3; CANCA; C-ANCA
• Gene ID: 5657
• mRNA Refseq: NM_002777
• Protein Refseq: NP_002768
• MIM: 177020
• UniProt ID: P24158