Recombinant Human PSAP protein, GST-tagged
Cat.No. : | PSAP-257H |
Product Overview : | Recombinant Human PSAP(1 a.a. - 524 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 83.16 kDa |
AA Sequence : | MYALFLLASLLGAALAGPVLGLKEC TRGSAVWCQNVKTASDCGAVKHCLQ TVWNKPTVKSLPCDICKDVVTAAGD MLKDNATEEEILVYLEKTCDWLPKP NMSASCKEIVDSYLPVILDIIKGEM SRPGEVCSALNLCESLQKHLAELNH QKQLESNKIPELDITEVVAPFMANI PLLLYPQDGPRSKPQPKDNGDVCQD CIQMVTDIQTAVRTNSTFVQALVEH VKEECDRLGPGMADICKNYISQYSE IAIQMMMHMQPKEICALVGFCDEVK EMPMQTLVPAKVASKNVIPALELVE PIKKHEVPAKSDVYCEVCEFLVKEV TKLIDNNKTEKEILDAFDKMCSKLP KSLSEECQEVVDTYGSSILSILLEE VSPELVCSMLHLCSGTRLPALTVHV TQPKDGGFCEVCKKLVGYLDRNLEK NSTKQEILAALEKGCSFLPDPYQKQ CDQFVAEYEPVLIEILVEVMDPSFV CLKIGACPLAHKPLLGTEKCIWGPS YWCQNTETAAQCNAVEHCKRHVWN |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade Aliquot to avoid repeated freezing and thawing. |
Gene Name : | PSAP prosaposin [ Homo sapiens ] |
Official Symbol : | PSAP |
Synonyms : | PSAP; prosaposin; GLBA, SAP1, sphingolipid activator protein 1; proactivator polypeptide; variant Gaucher disease and variant metachromatic leukodystrophy; sphingolipid activator protein-1; GLBA; SAP1; FLJ00245; MGC110993; |
Gene ID : | 5660 |
mRNA Refseq : | NM_002778 |
Protein Refseq : | NP_002769 |
MIM : | 176801 |
UniProt ID : | P07602 |
Chromosome Location : | 10q21-q22 |
Pathway : | Glycosphingolipid metabolism, organism-specific biosystem; Hemostasis, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; |
Function : | enzyme activator activity; lipid binding; |
Products Types
◆ Recombinant Protein | ||
PSAP-01H | Recombinant Human PSAP Protein, His-tagged | +Inquiry |
PSAP-4415R | Recombinant Rat PSAP Protein, His (Fc)-Avi-tagged | +Inquiry |
PSAP-7197M | Recombinant Mouse PSAP Protein, His (Fc)-Avi-tagged | +Inquiry |
PSAP-5504H | Recombinant Human PSAP protein, His-tagged | +Inquiry |
PSAP-13538M | Recombinant Mouse PSAP Protein | +Inquiry |
◆ Lysates | ||
PSAP-2793HCL | Recombinant Human PSAP 293 Cell Lysate | +Inquiry |
PSAP-2792HCL | Recombinant Human PSAP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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