"PSG6" Related Products

Recombinant Human PSG6 protein, His-tagged

Cat.No.: PSG6-201H
Product Overview: Recombinant Human PSG6(Gln35-His424) fused with His tag at C-terminal was expressed in HEK293.
Description: Pregnancy-specific glycoprotein 6 (PSG-6), also known as PSG10 and PSGGB is a secreted glycoprotein of the PSG family within the CEA (carcinoembryonic antigen) superfamily. Mature human PSG-6 is a 401 amino acid (aa) protein that consists of four tandem immunoglobulin-like domains followed by a 30 aa C-terminal tail. The N-terminal Ig-like domain contains an Arg-Gly-Asp (RGD) sequence which is a consensus integrin-binding motif found in many adhesion proteins. Alternative splicing generates an additional isoform with a substitution in the C-terminal tail. PSG-6 is predominantly expressed in placenta and more weakly in granulocytes. It induces monocyte production of the cytokines IL-6, IL-10, and TGF-beta 1.
Source: HEK293
Species: Human
Tag : His
Predicted N Terminal: No results obtained. Gln35 inferred from enzymatic pyroglutamate treatment revealing Val36
Form: Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity: Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.9-4.5 μg/mL.
Molecular Mass: Predicted Molecular Mass: 45 kDa
SDS-PAGE: 62-73 kDa, reducing conditions
Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.
Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution: Reconstitute at 500 μg/mL in PBS.
Gene Name: PSG6 pregnancy specific beta-1-glycoprotein 6 [ Homo sapiens ]
Official Symbol: PSG6
Synonyms: PSG6; pregnancy specific beta-1-glycoprotein 6; pregnancy-specific beta-1-glycoprotein 6; PS-beta-G-6; PS-beta-G-10; PS-beta-G-12; pregnancy-specific beta-1-glycoprotein 10; pregnancy-specific beta-1-glycoprotein 12; PSG10; PSBG-6; PSBG-10; PSBG-12;
Gene ID: 5675
mRNA Refseq: NM_001031850
Protein Refseq: NP_001027020
MIM: 176395
UniProt ID: Q00889

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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