| Gene Name |
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 [ Homo sapiens ] |
| Official Symbol |
PSMA3 |
| Synonyms |
PSMA3; proteasome (prosome, macropain) subunit, alpha type, 3; proteasome subunit alpha type-3; HC8; macropain subunit C8; proteasome subunit C8; proteasome component C8; multicatalytic endopeptidase complex subunit C8; PSC3; MGC12306; MGC32631; |
| Gene ID |
5684 |
| mRNA Refseq |
NM_002788 |
| Protein Refseq |
NP_002779 |
| MIM |
176843 |
| UniProt ID |
P25788 |
| Chromosome Location |
14q23 |
| Pathway |
APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; |
| Function |
peptidase activity; protein binding; threonine-type endopeptidase activity; |