Recombinant Human PSMA6 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PSMA6 Protein, Myc/DDK-tagged, C13 and N15-labeled

PSMA6 Related Products

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Cat.No. : PSMA6-4556H
Product Overview : PSMA6 MS Standard C13 and N15-labeled recombinant protein (NP_002782) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 27.4 kDa
AA Sequence : MSRGSSAGFD RHITIFSPEG RLYQVEYAFK AINQGGLTSV AVRGKDCAVI VTQKKVPDKL LDSSTVTHLF KITENIGCVM TGMTADSRSQ VQRARYEAAN WKYKYGYEIP VDMLCKRIAD ISQVYTQNAE MRPLGCCMIL IGIDEEQGPQ VYKCDPAGYY CGFKATAAGV KQTESTSFLE KKVKKKFDWT FEQTVETAIT CLSTVLSIDF KPSEIEVGVV TVENPKFRIL TEAEIDAHLV ALAERDTRTR PLEQKLISEE DLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PSMA6 proteasome 20S subunit alpha 6 [ Homo sapiens (human) ]
Official Symbol : PSMA6
Synonyms : PSMA6; proteasome (prosome, macropain) subunit, alpha type, 6; proteasome subunit alpha type-6; IOTA; MGC2333; MGC22756; MGC23846; p27K; PROS27; PROS-27; macropain iota chain; prosomal P27K protein; proteasome iota chain; macropain subunit iota; 27 kDa prosomal protein; proteasome subunit iota; multicatalytic endopeptidase complex iota chain;
Gene ID : 5687
mRNA Refseq : NM_002791
Protein Refseq : NP_002782
MIM : 602855
UniProt ID : P60900

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