Gene Name |
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 [ Homo sapiens ] |
Official Symbol |
PSMC2 |
Synonyms |
PSMC2; proteasome (prosome, macropain) 26S subunit, ATPase, 2; 26S protease regulatory subunit 7; mammalian suppressor of sgv 1 of yeast; MSS1; Nbla10058; protease 26S subunit 7; proteasome 26S subunit; ATPase; 2; putative protein product of Nbla10058; S7; proteasome 26S subunit ATPase 2; proteasome 26S subunit, ATPase, 2; 26S proteasome AAA-ATPase subunit RPT1; mammalian suppressor of sgv-1 of yeast; MGC3004; |
Gene ID |
5701 |
mRNA Refseq |
NM_001204453 |
Protein Refseq |
NP_001191382 |
MIM |
154365 |
UniProt ID |
P35998 |
Chromosome Location |
7q22.1-q22.3 |
Pathway |
APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; |
Function |
ATP binding; ATPase activity; hydrolase activity; nucleotide binding; protein binding; |