Recombinant Human PSMC6, T7-tagged

• Cat.No.: PSMC6-398H
• Product Overview: Recombinant Human PSMC6 was expressed inE.Coliusing an N-terminal T7 tag. MW=44.7 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Description: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 α subunits and 2 rings are composed of 7 β subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.
• Sequence: 1-389.
• Purity: ~95%.
• Specific Activity: n/aH.
• Applications: This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
• Buffer: 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.
• Storage: Store at -70˚C. As with any protein, exposing PSMC6 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• SDS-PAGE: SDS PAGE Analysis of PSMC6 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining.

Gene Information

• Gene Name: PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 [ Homo sapiens ]
• Synonyms: PSMC6; proteasome (prosome, macropain) 26S subunit, ATPase, 6; P44; p42; SUG2; CADP44; MGC12520; proteasome 26S ATPase subunit 6; proteasome subunit p42; conserved ATPase domain protein 44; 26S protease regulatory subunit S10B
• Gene ID: 5706
• mRNA Refseq: NM_002806
• Protein Refseq: NP_002797
• MIM: 602708
• UniProt ID: P62333
• Chromosome Location: 14q22.1
• Pathway: Proteasome; Apoptosis; Cell Cycle Checkpoints; Cell Cycle, Mitotic; DNA Replication; HIV Infection; Metabolism of amino acids; Signaling by Wnt
• Function: ATP binding; ATPase activity; hydrolase activity; nucleotide binding; protein binding, bridging