Recombinant Human PTCH1 Protein, DDK-tagged
Cat.No. : | PTCH1-414H |
Product Overview : | Recombinant Human PTCH1(Met-Arg770-Trp1027), transcript variant 1b, fused with DDK tag at C-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. |
Source : | Insect cells |
Species : | Human |
Tag : | DDK |
Form : | 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. |
Molecular Mass : | 30.4 kDa |
Protein length : | Met-Arg770-Trp1027 |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | PTCH1 patched 1 [ Homo sapiens ] |
Official Symbol : | PTCH1 |
Synonyms : | PTCH1; patched 1; NBCCS, patched (Drosophila) homolog , patched homolog (Drosophila) , patched homolog 1 (Drosophila) , PTCH; protein patched homolog 1; BCNS; PTCH protein +4; PTCH protein -10; PTCH protein +12b; patched homolog 1; PTCH protein -3,4,5; PTC; HPE7; PTC1; PTCH; NBCCS; PTCH11; FLJ26746; FLJ42602; |
Gene ID : | 5727 |
mRNA Refseq : | NM_000264 |
Protein Refseq : | NP_000255 |
MIM : | 601309 |
UniProt ID : | Q13635 |
Products Types
◆ Recombinant Protein | ||
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PTCH1-13624M | Recombinant Mouse PTCH1 Protein | +Inquiry |
◆ Lysates | ||
PTCH1-2723HCL | Recombinant Human PTCH1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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