Recombinant Human PTGDS Protein, Myc/DDK-tagged, C13 and N15-labeled PTGDS-993H

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Recombinant Human PTGDS Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	PTGDS-993H
Product Overview :	PTGDS MS Standard C13 and N15-labeled recombinant protein (NP_000945) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	20.8 kDa
AA Sequence :	MATHHTLWMG LALLGVLGDL QAAPEAQVSV QPNFQQDKFL GRWFSAGLAS NSSWLREKKA ALSMCKSVVA PATDGGLNLT STFLRKNQCE TRTMLLQPAG SLGSYSYRSP HWGSTYSVSV VETDYDQYAL LYSQGSKGPG EDFRMATLYS RTQTPRAELK EKFTAFCKAQ GFTEDTIVFL PQTDKCMTEQ TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	PTGDS prostaglandin D2 synthase [ Homo sapiens (human) ]
Official Symbol :	PTGDS
Synonyms :	PTGDS; prostaglandin D2 synthase 21kDa (brain); prostaglandin D2 synthase (21kD, brain); prostaglandin-H2 D-isomerase; L PGDS; lipocalin type prostaglandin D synthase; PGDS; cerebrin-28; PGD2 synthase; beta-trace protein; prostaglandin D synthase; prostaglandin-D2 synthase; glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; lipocalin-type prostaglandin-D synthase; PDS; PGD2; LPGDS; PGDS2; L-PGDS;
Gene ID :	5730
mRNA Refseq :	NM_000954
Protein Refseq :	NP_000945
MIM :	176803
UniProt ID :	P41222