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Recombinant Human PTH2R protein

Cat.No. : PTH2R-32H
Product Overview : Recombinant Human PTH2R was expressed in Wheat Germ.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants.
Source : Wheat Germ
Species : Human
Form : 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
Molecular Mass : 60.5 kDa
AA Sequence : MAGLGASLHVWGWLMLGSCLLARAQ LDSDGTITIEEQIVLVLKAKVQCEL NITAQLQEGEGNCFPEWDGLICWPR GTVGKISAVPCPPYIYDFNHKGVAF RHCNPNGTWDFMHSLNKTWANYSDC LRFLQPDISIGKQEFFERLYVMYTV GYSISFGSLAVAILIIGYFRRLHCT RNYIHMHLFVSFMLRATSIFVKDRV VHAHIGVKELESLIMQDDPQNSIEA TSVDKSQYIGCKIAVVMFIYFLATN YYWILVEGLYLHNLIFVAFFSDTKY LWGFILIGWGFPAAFVAAWAVARAT LADARCWELSAGDIKWIYQAPILAA IGLNFILFLNTVRVLATKIWETNAV GHDTRKQYRKLAKSTLVLVLVFGVH YIVFVCLPHSFTGLGWEIRMHCELF FNSFQGFFVSIIYCYCNGEVQAEVK KMWSRWNLSVDWKRTPPCGSRRCGS VLTTVTHSTSSQSQVAASTRMVLIS GKAAKIASRQPDSHITLPGYVWSNS EQDCLPHSFHEETKEDSGRQGDDIL MEKPSRPMESNPDTEGCQGETEDVL
Applications : Antibody Production; Functional Study; Compound Screening
Notes : Heating may cause protein aggregation. Please do not heat this product before electrophoresis. Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : PTH2R parathyroid hormone 2 receptor [ Homo sapiens ]
Official Symbol : PTH2R
Synonyms : PTH2R; parathyroid hormone 2 receptor; parathyroid hormone receptor 2 , PTHR2; PTH2 receptor; parathyroid hormone receptor 2; PTHR2;
Gene ID : 5746
mRNA Refseq : NM_005048
Protein Refseq : NP_005039
MIM : 601469
UniProt ID : P49190
Chromosome Location : 2q33
Pathway : Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function : parathyroid hormone receptor activity; receptor activity; signal transducer activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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