| Description : |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
41 kDa |
| AA Sequence : |
MPTTIEREFEELDTQRRWQPLYLEI RNESHDYPHRVAKFPENRNRNRYRD VSPYDHSRVKLQNAENDYINASLVD IEEAQRSYILTQGPLPNTCCHFWLM VWQQKTKAVVMLNRIVEKESVKCAQ YWPTDDQEMLFKETGFSVKLLSEDV KSYYTVHLLQLENINSGETRTISHF HYTTWPDFGVPESPASFLNFLFKVR ESGSLNPDHGPAVIHCSAGIGRSGT FSLVDTCLVLMEKGDDINIKQVLLN MRKYRMGLIQTPDQLRFSYMAIIEG AKCIKGDSSIQKRWKELSKEDLSPA FDHSPNKIMTEKYNGNRIGLEEEKL TGDRCTGLSSKMQDTMEENSERPRL TDTTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
