"PTPRN" Related Products


Recombinant Human PTPRN Protein, DDK-tagged

Cat.No. : PTPRN-675H
Product Overview : Recombinant Human PTPRN(Met-Val35-Arg575), transcript variant 1, fused with DDK tag at C-terminal was expressed in insect cells.
Description : The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Source : Insect cells
Species : Human
Tag : DDK
Form : 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Molecular Mass : 57.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PTPRN protein tyrosine phosphatase, receptor type, N [ Homo sapiens ]
Official Symbol : PTPRN
Synonyms : PTPRN; protein tyrosine phosphatase, receptor type, N; receptor-type tyrosine-protein phosphatase-like N; IA 2; ICA 512; PTP IA-2; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine phosphatase-like N; IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP; FLJ16131;
Gene ID : 5798
mRNA Refseq : NM_001199763
Protein Refseq : NP_001186692
MIM : 601773
UniProt ID : Q16849

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