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Recombinant Human PTPRN Protein, His-tagged

Cat.No. : PTPRN-676H
Product Overview : Recombinant Human PTPRN, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : His
Form : Supplied as a 0.2 µM filtered solution of 20mM Tris, 150mM NaCl, pH8.0
Molecular Mass : 35.6kD
AA Sequence : MGSSHHHHHHSSGLVPRGSHMDIST GHMILAYMEDHLRNRDRLAKEWQAL CAYQAEPNTCATAQGEGNIKKNRHP DFLPYDHARIKLKVESSPSRSDYIN ASPIIEHDPRMPAYIATQGPLSHTI ADFWQMVWESGCTVIVMLTPLVEDG VKQCDRYWPDEGASLYHVYEVNLVS EHIWCEDFLVRSFYLKNVQTQETRT LTQFHFLSWPAEGTPASTRPLLDFR RKVNKCYRGRSCPIIVHCSDGAGRT GTYIL
Endotoxin : Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Gene Name : PTPRN protein tyrosine phosphatase, receptor type, N [ Homo sapiens ]
Official Symbol : PTPRN
Synonyms : PTPRN; protein tyrosine phosphatase, receptor type, N; receptor-type tyrosine-protein phosphatase-like N; IA 2; ICA 512; PTP IA-2; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine phosphatase-like N; IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP; FLJ16131;
Gene ID : 5798
mRNA Refseq : NM_001199763
Protein Refseq : NP_001186692
MIM : 601773
UniProt ID : Q16849

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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