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Recombinant Human PVR Protein, MYC/DDK-tagged

Cat.No.: PVR-3157H
Product Overview: Recombinant Human PVR protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Source: HEK293
Species: Human
Tag : MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 39.1 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: PVR poliovirus receptor [ Homo sapiens ]
Official Symbol: PVR
Synonyms: CD155; HVED; Necl-5; NECL5; PVS; TAGE4
Gene ID: 5817
mRNA Refseq: NM_001135768
Protein Refseq: NP_001129240
MIM: 173850
UniProt ID: P15151

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