Recombinant Human PVR Protein (Trp21-Asn343), C-mFc and 6×His-tagged

• Cat.No.: PVR-559H
• Product Overview: Recombinant Human PVR Protein (Trp21-Asn343) with C-mFc and 6×His tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: C-mFc and 6×His
• Form: Lyophilized
• Molecular Mass: 62.2 kDa
• Protein Length: Trp21-Asn343
• Purity: > 95% as determined by SDS-PAGE and Coomassie blue staining.
• Storage: Store at -80 centigrade for 12 months (Avoid repeated freezing and thawing)
• Storage Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 34 % trehalose is added as protectants before lyophilization.

Gene Information

• Gene Name: PVR poliovirus receptor [ Homo sapiens (human) ]
• Official Symbol: PVR
• Synonyms: PVR; poliovirus receptor; PVS; CD155; HVED; Necl 5; NECL5; nectin like 5; Tage4; nectin-like 5; nectin-like protein 5; TAGE4; Necl-5; FLJ25946
• Gene ID: 5817
• mRNA Refseq: NM_001135768
• Protein Refseq: NP_001129240
• MIM: 173850
• UniProt ID: P15151