Recombinant Human PVRIG protein, His-Avi-tagged

• Cat.No.: PVRIG-617H
• Product Overview: Human PVRIG Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Thr41-Asp171.

Specification

• Description: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 16.3KDa.
• Protein length: Thr41-Asp171
• Endotoxin: Less than 1EU per ug by the LAL method.
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: PVRIG PVR related immunoglobulin domain containing [ Homo sapiens (human) ]
• Official Symbol: PVRIG
• Synonyms: C7orf15; C7orf15MGC138295; CD112R; MGC104322; MGC138297; MGC2463; poliovirus receptor related immunoglobulin domain containing; Poliovirus receptor-related immunoglobulin domain-containing protein; PVRIG; transmembrane protein PVRIG
• Gene ID: 79037
• mRNA Refseq: NM_024070.3
• Protein Refseq: NP_076975.2
• MIM: 617012
• UniProt ID: Q6DKI7