| Description : |
This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
165.1 kDa |
| AA Sequence : |
MAKRSRGPGRRCLLALVLFCAWGTL AVVAQKPGAGCPSRCLCFRTTVRCM HLLLEAVPAVAPQTSILDLRFNRIR EIQPGAFRRLRNLNTLLLNNNQIKR IPSGAFEDLENLKYLYLYKNEIQSI DRQAFKGLASLEQLYLHFNQIETLD PDSFQHLPKLERLFLHNNRITHLVP GTFNHLESMKRLRLDSNTLHCDCEI LWLADLLKTYAESGNAQAAAICEYP RRIQGRSVATITPEELNCERPRITS EPQDADVTSGNTVYFTCRAEGNPKP EIIWLRNNNELSMKTDSRLNLLDDG TLMIQNTQETDQGIYQCMAKNVAGE VKTQEVTLRYFGSPARPTFVIQPQN TEVLVGESVTLECSATGHPPPRISW TRGDRTPLPVDPRVNITPSGGLYIQ NVVQGDSGEYACSATNNIDSVHATA FIIVQALPQFTVTPQDRVVIEGQTV DFQCEAKGNPPPVIAWTKGGSQLSV DRRHLVLSSGTLRISGVALHDQGQY ECQAVNIIGSQKVVAHLTVQPRVTP VFASIPSDTTVEVGANVQLPCSSQG EPEPAITWNKDGVQVTESGKFHISP EGFLTINDVGPADAGRYECVARNTI GSASVSMVLSVNVPDVSRNGDPFVA TSIVEAIATVDRAINSTRTHLFDSR PRSPNDLLALFRYPRDPYTVEQARA GEIFERTLQLIQEHVQHGLMVDLNG TSYHYNDLVSPQYLNLIANLSGCTA HRRVNNCSDMCFHQKYRTHDGTCNN LQHPMWGASLTAFERLLKSVYENGF NTPRGINPHRLYNGHALPMPRLVST TLIGTETVTPDEQFTHMLMQWGQFL DHDLDSTVVALSQARFSDGQHCSNV CSNDPPCFSVMIPPNDSRARSGARC MFFVRSSPVCGSGMTSLLMNSVYPR EQINQLTSYIDASNVYGSTEHEARS IRDLASHRGLLRQGIVQRSGKPLLP FATGPPTECMRDENESPIPCFLAGD HRANEQLGLTSMHTLWFREHNRIAT ELLKLNPHWDGDTIYYETRKIVGAE IQHITYQHWLPKILGEVGMRTLGEY HGYDPGINAGIFNAFATAAFRFGHT LVNPLLYRLDENFQPIAQDHLPLHK AFFSPFRIVNEGGIDPLLRGLFGVA GKMRVPSQLLNTELTERLFSMAHTV ALDLAAINIQRGRDHGIPPYHDYRV YCNLSAAHTFEDLKNEIKNPEIREK LKRLYGSTLNIDLFPALVVEDLVPG SRLGPTLMCLLSTQFKRLRDGDRLW YENPGVFSPAQLTQIKQTSLARILC DNADNITRVQSDVFRVAEFPHGYGS CDEIPRVDLRVWQDCCEDCRTRGQF NAFSYHFRGRRSLEFSYQEDKPTKK TRPRKIPSVGRQGEHLSNSTSAFST RSDASGTNDFREFVLEMQKTITDLR TQIKKLESRLSTTECVDAGGESHAN NTKWKKDACTICECKDGQVTCFVEA CPPATCAVPVNIPGACCPVCLQKRA EEKPTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
