| Description : |
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
87.8 kDa |
| AA Sequence : |
MAALDSLSLFTSLGLSEQKARETLK NSALSAQLREAATQAQQTLGSTIDK ATGILLYGLASRLRDTRRLSFLVSY IASKKIHTEPQLSAALEYVRSHPLD PIDTVDFERECGVGVIVTPEQIEEA VEAAINRHRPQLLVERYHFNMGLLM GEARAVLKWADGKMIKNEVDMQVLH LLGPKLEADLEKKFKVAKARLEETD RRTAKDVVENGETADQTLSLMEQLR GEALKFHKPGENYKTPGYVVTPHTM NLLKQHLEITGGQVRTRFPPEPNGI LHIGHAKAINFNFGYAKANNGICFL RFDDTNPEKEEAKFFTAICDMVAWL GYTPYKVTYASDYFDQLYAWAVELI RRGLAYVCHQRGEELKGHNTLPSPW RDRPMEESLLLFEAMRKGKFSEGEA TLRMKLVMEDGKMDPVAYRVKYTPH HRTGDKWCIYPTYDYTHCLCDSIEH ITHSLCTKEFQARRSSYFWLCNALD VYCPVQWEYGRLNLHYAVVSKRKIL QLVATGAVRDWDDPRLFTLTALRRR GFPPEAINNFCARVGVTVAQTTMEP HLLEACVRDVLNDTAPRAMAVLESL RVIITNFPAAKSLDIQVPNFPADET KGFHQVPFAPIVFIERTDFKEEPEP GFKRLAWGQPVGLRHTGYVIELQHV VKGPSGCVESLEVTCRRADAGEKPK AFIHWVSQPLMCEVRLYERLFQHKN PEDPTEVPGGFLSDLNLASLHVVDA ALVDCSVALAKPFDKFQFERLGYFS VDPDSHQGKLVFNRTVTLKEDPGKV TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
