Recombinant Human QSOX1
Cat.No. : | QSOX1-31036TH |
Product Overview : | Recombinant fragment of Human Quiescin Q6 with an N terminal proprietary tag. Predicted MW 36.63kDa. |
- Specification
- Gene Information
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Description : | This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | KALAEDVKAWRPALYLAALDCAEET NSAVCRDFNIPGFPTVRFFKAFTKN GSGAVFPVAGADVQTLRERLIDALE SHHDTWPPACPPLEPAKLEEIDGFF |
Sequence Similarities : | Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.Contains 1 ERV/ALR sulfhydryl oxidase domain.Contains 1 thioredoxin domain. |
Gene Name : | QSOX1 quiescin Q6 sulfhydryl oxidase 1 [ Homo sapiens ] |
Official Symbol : | QSOX1 |
Synonyms : | QSOX1; quiescin Q6 sulfhydryl oxidase 1; QSCN6, quiescin Q6; sulfhydryl oxidase 1; |
Gene ID : | 5768 |
mRNA Refseq : | NM_001004128 |
Protein Refseq : | NP_001004128 |
MIM : | 603120 |
Uniprot ID : | O00391 |
Chromosome Location : | 1q24 |
Function : | flavin-linked sulfhydryl oxidase activity; flavin-linked sulfhydryl oxidase activity; oxidoreductase activity; |
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QSOX1-285H | Active Recombinant Human QSOX1 protein, His-tagged | +Inquiry |
QSOX1-5701C | Recombinant Chicken QSOX1 | +Inquiry |
QSOX1-2095H | Recombinant Human QSOX1, GST-tagged | +Inquiry |
◆ Lysates | ||
QSOX1-2635HCL | Recombinant Human QSOX1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThere is currently no specific treatment for QSOX1. However, drugs that target their associated signal transduction pathways or binding targets may have potential therapeutic value.
Recent studies have shown that QSOX1 may be associated with the occurrence and progression of cardiovascular disease. In atherosclerotic lesions, the expression level of QSOX1 may change, affecting the development of the lesion.
Recent studies have shown that QSOX1 may be involved in the development and progression of certain cancers. In addition, QSOX1 may also be associated with neurodegenerative diseases.
QSOX1 expression levels can be detected by gene sequencing, immunohistochemistry, and western blotting.
At present, there is insufficient research on whether QSOX1 can be used as a biomarker for cardiovascular disease, and further verification is needed.
There are multiple interactions between QSOX1 and other molecules and drugs. For example, QSOX1 can bind to specific cytokines, which affect the growth and differentiation of cells. In addition, some drugs can also affect QSOX1 expression levels or function.
Customer Reviews (3)
Write a reviewQSOX1 has good heat resistance and remains active when treated at high temperatures for a long time.
The safety is very high, so you can use it with confidence.
There are no complicated experimental procedures, making it suitable for novices.
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