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Recombinant Human RAB8A Protein, MYC/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | RAB8A-037H |
| Product Overview : | RAB8A MS Standard C13 and N15-labeled recombinant protein (NP_005361) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 23.7 kDa |
| AA Sequence : | MAKTYDYLFK LLLIGDSGVG KTCVLFRFSE DAFNSTFIST IGIDFKIRTI ELDGKRIKLQ IWDTAGQERF RTITTAYYRG AMGIMLVYDI TNEKSFDNIR NWIRNIEEHA SADVEKMILG NKCDVNDKRQ VSKERGEKLA LDYGIKFMET SAKANINVEN AFFTLARDIK AKMDKKLEGN SPQGSNQGVK ITPDQQKRSS FFRCVLLTRT RPLEQKLISE EDLAANDILD YKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | RAB8A RAB8A, member RAS oncogene family [ Homo sapiens (human) ] |
| Official Symbol : | RAB8A |
| Synonyms : | RAB8A; RAB8A, member RAS oncogene family; MEL; RAB8; ras-related protein Rab-8A; mel transforming oncogene (RAB8 homolog); mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; oncogene c-mel; ras-associated protein RAB8 |
| Gene ID : | 4218 |
| mRNA Refseq : | NM_005370 |
| Protein Refseq : | NP_005361 |
| MIM : | 165040 |
| UniProt ID : | P61006 |
◆ Recombinant Protein
| Rab8a-5332M | Recombinant Mouse Rab8a Protein, Myc/DDK-tagged | +Inquiry |
| RAB8A-29054TH | Recombinant Human RAB8A | +Inquiry |
| RAB8A-5636Z | Recombinant Zebrafish RAB8A | +Inquiry |
| RAB8A-345H | Recombinant Human RAB8A protein, MYC/DDK-tagged | +Inquiry |
| RAB8A-13839M | Recombinant Mouse RAB8A Protein | +Inquiry |
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◆ Lysates
| RAB8A-2580HCL | Recombinant Human RAB8A 293 Cell Lysate | +Inquiry |
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RAB10RAB11ARab14Rab17Rab18Rab19RAB1ARAB1BRAB21RAB22ARab23Rab24Rab27aRAB27BRAB31RAB32RAB34RAB37Rab3aRAB3BRAB3CRAB4ARAB4BRab5aRAB5BRAB6ARAB6BRAB7ARAB9ARAB13RAB2ARAB3DRAB15RAB25RAB26RAB2BRAB33ARAB33BRAB36RAB38RAB39BRAB42RAB43RAB7BRAB7L1RAB8ARAB11BRAB11FIP5RAB28RAB40BRAB8BRAB9BRAB30RAB35RAB11FIP3RAB11FIP2RAB3IL1RAB3IPRAB11FIP1RAB11FIP4RAB20RAB39RAB40ARAB40CRAB41RAB5CRAB3GAP2RAB3GAP1RAB6CRAB12RAB39ARab1Rab9RAB40ALRab44
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