Recombinant Human RACGAP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human RACGAP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : RACGAP1-4699H
Product Overview : RACGAP1 MS Standard C13 and N15-labeled recombinant protein (NP_001119575) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 71 kDa
AA Sequence : MDTMMLNVRN LFEQLVRRVE ILSEGNEVQF IQLAKDFEDF RKKWQRTDHE LGKYKDLLMK AETERSALDV KLKHARNQVD VEIKRRQRAE ADCEKLERQI QLIREMLMCD TSGSIQLSEE QKSALAFLNR GQPSSSNAGN KRLSTIDESG SILSDISFDK TDESLDWDSS LVKTFKLKKR EKRRSTSRQF VDGPPGPVKK TRSIGSAVDQ GNESIVAKTT VTVPNDGGPI EAVSTIETVP YWTRSRRKTG TLQPWNSDST LNSRQLEPRT ETDSVGTPQS NGGMRLHDFV SKTVIKPESC VPCGKRIKFG KLSLKCRDCR VVSHPECRDR CPLPCIPTLI GTPVKIGEGM LADFVSQTSP MIPSIVVHCV NEIEQRGLTE TGLYRISGCD RTVKELKEKF LRVKTVPLLS KVDDIHAICS LLKDFLRNLK EPLLTFRLNR AFMEAAEITD EDNSIAAMYQ AVGELPQANR DTLAFLMIHL QRVAQSPHTK MDVANLAKVF GPTIVAHAVP NPDPVTMLQD IKRQPKVVER LLSLPLEYWS QFMMVEQENI DPLHVIENSN AFSTPQTPDI KVSLLGPVTT PEHQLLKTPS SSSLSQRVRS TLTKNTPRFG SKSKSATNLG RQGNFFASPM LKTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : RACGAP1 Rac GTPase activating protein 1 [ Homo sapiens (human) ]
Official Symbol : RACGAP1
Synonyms : RACGAP1; Rac GTPase activating protein 1; rac GTPase-activating protein 1; MgcRacGAP; protein CYK4 homolg; male germ cell RacGap; GTPase activating protein; CYK4; ID-GAP; HsCYK-4;
Gene ID : 29127
mRNA Refseq : NM_001126103
Protein Refseq : NP_001119575
MIM : 604980
UniProt ID : Q9H0H5

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