Recombinant Human RAD51 (G151D) Mutation Protein, Trx/His-tagged
Cat.No. : | RAD1-01H |
Product Overview : | Recombinant Human RAD51 (G151D) Mutation Protein with a Trx/His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | Trx/His |
Molecular Mass : | 54 kDa |
AA Sequence : | MSDKIIHLTDDSFDTDVLKADGAIL VDFWAEWCGPCKMIAPILDEIADEY QGKLTVAKLNIDQNPGTAPKYGIRG IPTLLLFKNGEVAATKVGALSKGQL KEFLDANLAGSGSGHMHHHHHHSSG LVPRGSGMKETAAAKFERQHMDSPD LGTDDDDKMAMQMQLEANADTSVEE ESFGPQPISRLEQCGINANDVKKLE EAGFHTVEAVAYAPKKELINIKGIS EAKADKILTESRSVARLECNSVILV YCTLRLSGSSDSPASASRVVGTTGG IETGSITEMFGEFRTGKTQICHTLA VTCQLPIDRDGGEGKAMYIDTEGTF RPERLLAVAERYGLSGSDVLDNVAY ARAFNTDHQTQLLYQASAMMVESRY ALLIVDSATALYRTDYSGRGELSAR QMHLARFLRMLLRLADEFGVAVVIT NQVVAQVDGAAMFAADPKKPIGGNI IAHASTTRLYLRKGRGETRICKIYD SPCLPEAEAMFAINADGVGDAKD |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.2 mg/mL |
Storage Buffer : | PBS buffer |
Gene Name : | RAD51 RAD51 recombinase [ Homo sapiens (human) ] |
Official Symbol : | RAD51 |
Synonyms : | RAD51; RAD51 recombinase; RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930; DNA repair protein RAD51 homolog 1; BRCA1/BRCA2-containing complex, subunit 5; RAD51 homolog A; RecA, E. coli, homolog of; RecA-like protein; recombination protein A |
Gene ID : | 5888 |
mRNA Refseq : | NM_133487 |
Protein Refseq : | NP_597994 |
MIM : | 179617 |
UniProt ID : | Q06609 |
Products Types
◆ Recombinant Protein | ||
RAD51-03H | Recombinant Human RAD51 Protein (G151D mutated), Sumo/His/Strep tagged | +Inquiry |
Rad51-5350M | Recombinant Mouse Rad51 Protein, Myc/DDK-tagged | +Inquiry |
RAD51-01H | Recombinant Human RAD51 (G151D) Mutation Protein, Trx/His-tagged | +Inquiry |
RAD51-125H | Recombinant Human RAD51 Protein, Myc/DDK-tagged | +Inquiry |
RAD1-02H | Recombinant Human RAD51 (G151D) Mutation Protein | +Inquiry |
◆ Lysates | ||
RAD51-2556HCL | Recombinant Human RAD51 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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