Recombinant Human RAN (E70A) Protein

• Cat.No.: RAN-719H
• Product Overview: Recombinant Human RAN protein (NM_006325, E70A) was expressed in E. coli.

Specification

• Description: Ran (Ras-related nuclear protein, TC4) belongs to the Ras superfamily of GTP binding proteins. It acts in cellular processes such as nuclear transport, mitotic spindle assembly, and post-mitotic nuclear assembly. The mutation E70A results in inhibition of the guanine exchange reaction mediated by RCC1, the guanine nucleotide exchange factor (GEF) for Ran. Protein preparation is 85% GDP-loaded, measured by HPLC.
• Source: E. coli
• Species: Human
• Form: 20 mM KH2PO4/K2HPO4 pH 7.4, 1 mM DTE and 5 mM MgCl2
• Molecular Mass: 24.0 kDa
• Protein length: 216 amino acids
• Purity: > 95 % (SDS-PAGE)
• Storage: Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Information

• Gene Name: RAN RAN, member RAS oncogene family [ Homo sapiens ]
• Official Symbol: RAN
• Synonyms: TC4; Gsp1; ARA24
• Gene ID: 5901
• mRNA Refseq: NM_006325.3
• Protein Refseq: NP_006316.1
• MIM: 601179
• UniProt ID: P62826