Recombinant Human RAN (G19V/Q69L) Protein


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Recombinant Human RAN (G19V/Q69L) Protein

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Cat.No. : RAN-718H
Product Overview : Recombinant Human RAN protein (NM_006325, G19V/Q69L) was expressed in E. coli .
Description : Ran belongs to the Ras superfamily of GTP binding proteins. It acts in cellular processes such as nuclear transport, mitotic spindle assembly, and post-mitotic nuclear assembly. The mutation Q69L abolishes GTP hydrolysis. The mutation G19V results in a gain-of-function mutant that is not, however, sensitive to the exchange factor RCC1. Protein preparation is 19% GDP-loaded, measured by HPLC.
Source : E. coli
Species : Human
Form : 50 mM KH2PO4/K2HPO4 pH 7.0, 6.5 mM DTE, 150 mM KCl and 5 mM MgCl2
Molecular Mass : 24.0 kDa
Protein length : 216 amino acids
Purity : > 95 % (SDS-PAGE)
Storage : Store at -80 centigrade, avoid freeze/thaw cycles.
Gene Name : RAN RAN, member RAS oncogene family [ Homo sapiens ]
Official Symbol : RAN
Synonyms : TC4; Gsp1; ARA24
Gene ID : 5901
mRNA Refseq : NM_006325.3
Protein Refseq : NP_006316.1
MIM : 601179
UniProt ID : P62826

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