| Cat.No. : |
RAN-718H |
| Product Overview : |
Recombinant Human RAN protein (NM_006325, G19V/Q69L) was expressed in E. coli . |
| Description : |
Ran belongs to the Ras superfamily of GTP binding proteins. It acts in cellular processes such as nuclear transport, mitotic spindle assembly, and post-mitotic nuclear assembly. The mutation Q69L abolishes GTP hydrolysis. The mutation G19V results in a gain-of-function mutant that is not, however, sensitive to the exchange factor RCC1. Protein preparation is 19% GDP-loaded, measured by HPLC. |
| Source : |
E. coli |
| Species : |
Human |
| Form : |
50 mM KH2PO4/K2HPO4 pH 7.0, 6.5 mM DTE, 150 mM KCl and 5 mM MgCl2 |
| Molecular Mass : |
24.0 kDa |
| Protein length : |
216 amino acids |
| Purity : |
> 95 % (SDS-PAGE) |
| Storage : |
Store at -80 centigrade, avoid freeze/thaw cycles. |
