| Description : |
This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
79.9 kDa |
| AA Sequence : |
MFGRKRSVSFGGFGWIDKTMLASLK VKKQELANSSDATLPDRPLSPPLTA PPTMKSSEFFEMLEKMQGIKLEEQK PGPQKNKDDYIPYPSIDEVVEKGGP YPQVILPQFGGYWIEDPENVGTPTS LGSSICEEEEEDNLSPNTFGYKLEC KGEARAYRRHFLGKDHLNFYCTGSS LGNLILSVKCEEAEGIEYLRVILRS KLKTVHERIPLAGLSKLPSVPQIAK AFCDDAVGLRFNPVLYPKASQMIVS YDEHEVNNTFKFGVIYQKARQTLEE ELFGNNEESPAFKEFLDLLGDTITL QDFKGFRGGLDVTHGQTGVESVYTT FRDREIMFHVSTKLPFTDGDAQQLQ RKRHIGNDIVAIIFQEENTPFVPDM IASNFLHAYIVVQVETPGTETPSYK VSVTAREDVPTFGPPLPSPPVFQKG PEFREFLLTKLTNAENACCKSDKFA KLEDRTRAALLDNLHDELHAHTQAM LGLGPEEDKFENGGHGGFLESFKRA IRVRSHSMETMVGGQKKSHSGGIPG SLSGGISHNSMEVTKTTFSPPVVAA TVKNQSRSPIKRRSGLFPRLHTGSE GQGDSRARCDSTSSTPKTPDGGHSS QEIKSETSSNPSSPEICPNKEKPFM KLKENGRAISRSSSSTSSVSSTAGE GEAMEEGDSGGSQPSTTSPFKQEVF VYSPSPSSESPSLGAAATPIIMSRS PTDAKSRNSPRSNLKFRFDKLSHAS SGAGHTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
