Description : |
This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
72.7 kDa |
AA Sequence : |
MEQLSDEEIDHGAEEDSDKEDQDLD KMFGAWLGELDKLTQSLDSDKPMEP VKRSPLRQETNMANFSYRFSIYNLN EALNQGETVDLDALMADLCSIEQEL SSIGSGNSKRQITETKATQKLPVSR HTLKHGTLKGLSSSSNRIAKPSHAS YSLDDVTAQLEQASLSMDEAAQQSV LEDTKPLVTNQHRRTASAGTVSDAE VHSISNSSHSSITSAASSMDSLDID KVTRPQELDLTHQGQPITEHAISLR CSSKQAKRHIDFTEEQAELTPHSYL DRETSLLLRNIAGKPSHLLTKEEQA AKLKAEKIRVALEKIKEAQVKKLVI RVHMSDDSSKTMMVDERQTVRQVLD NLMDKSHCGYSLDWSLVETVSELQM ERIFEDHENLVENLLNWTRDSQNKL IFMERIEKYALFKNPQNYLLGKKET AEMADRNKEVLLEECFCGSSVTVPE IEGVLWLKDDGKKSWKKRYFLLRAS GIYYVPKGKAKVSRDLVCFLQLDHV NVYYGQDYRNKYKAPTDYCLVLKHP QIQKKSQYIKYLCCDDVRTLHQWVN GIRIAKYGKQLYMNYQEALKRTESA YDWTSLSSSSIKSGSSSSSIPESQS NHSNQSDSGVSDTQPAGHVRSQSIV SSVFSEAWKRGTQLEESSKTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |