| Description : |
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
50.3 kDa |
| AA Sequence : |
MATNKERLFAAGALGPGSGYPGAGF PFAFPGALRGSPPFEMLSPSFRGLG QPDLPKEMASLSVETQSTSSEEMVP SSPSPPPPPRVYKPCFVCNDKSSGY HYGVSSCEGCKGFFRRSIQKNMVYT CHRDKNCIINKVTRNRCQYCRLQKC FEVGMSKEAVRNDRNKKKKEVKEEG SPDSYELSPQLEELITKVSKAHQET FPSLCQLGKYTTNSSADHRVQLDLG LWDKFSELATKCIIKIVEFAKRLPG FTGLSIADQITLLKAACLDILMLRI CTRYTPEQDTMTFSDGLTLNRTQMH NAGFGPLTDLVFAFAGQLLPLEMDD TETGLLSAICLICGDRMDLEEPEKV DKLQEPLLEALRLYARRRRPSQPYM FPRMLMKITDLRGISTKGAERAITL KMEIPGPMPPLIREMLENPEMFEDD SSQPGPHPNASSEDEVPGGQGKGGL KSPATRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
