Recombinant Human RB1 protein, His-GST-tagged
Cat.No. : | RB1-902H |
Product Overview : | Recombinant Human RB1 protein is produced by E. coli expression system. This protein is fused with a His-GST tag at the N-terminal. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | His-GST |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 49.2 kDa |
Protein length : | Gln639-Thr778 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | RB1 retinoblastoma 1 [ Homo sapiens ] |
Official Symbol : | RB1 |
Synonyms : | RB1; retinoblastoma 1; retinoblastoma-associated protein; RB; retinoblastoma suspectibility protein; pRb; OSRC; pp110; p105-Rb; |
Gene ID : | 5925 |
mRNA Refseq : | NM_000321 |
Protein Refseq : | NP_000312 |
MIM : | 614041 |
UniProt ID : | P06400 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (7)
Ask a questionMutations in RB1 lead to retinoblastoma and increase the risk of other cancers, disrupting normal cell cycle control.
RB1 interacts with transcription factors to regulate gene expression, impacting various cellular processes.
RB1 plays a crucial role in the DNA damage response, facilitating repair and maintaining genomic stability.
RB1 controls the G1 to S phase transition in the cell cycle, preventing unregulated cell division.
Changes in RB1 function affect stem cell differentiation and tissue regeneration, influencing tissue maintenance and repair.
RB1 influences cellular senescence and apoptosis, playing a role in aging and cell turnover.
As a tumor suppressor, RB1 prevents excessive cell proliferation and contributes to cancer prevention.
Customer Reviews (3)
Write a reviewEfficient protein purification, delivers consistent yield and purity.
Expertise in protein engineering, a trusted resource for research.
Reliable protein crystallization services, exceptional results achieved.
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