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Recombinant Human RBFOX1 Protein, His-tagged

Cat.No. : RBFOX1-657H
Product Overview : Recombinant human RBFOX1 protein, fused to His tag at N-terminus, was expressed in E. coli.
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Description : The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Source : E. coli
Species : Human
Tag : His
Form : 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
Molecular Mass : 42.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : RNA binding protein, fox-1 homolog 1[ Homo sapiens ]
Official Symbol : RBFOX1
Synonyms : 2BP1; A2BP1; FOX-1; FOX1; HRNBP1
Gene ID : 54715
mRNA Refseq : NM_018723.3
Protein Refseq : NP_061193.2
MIM : 605104
UniProt ID : Q9NWB1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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