Recombinant Human RBM38 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human RBM38 Protein, Myc/DDK-tagged, C13 and N15-labeled

RBM38 Related Products

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Cat.No. : RBM38-2815H
Product Overview : RBM38 MS Standard C13 and N15-labeled recombinant protein (NP_906270) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 12.7 kDa
AA Sequence : MLLQPAPCAP SAGFPRPLAA PGAMHGSQKD TTFTKIFVGG LPYHTTDASL RKYFEGFGDI EEAVVITDRQ TGKSRGYGFV TMADRAAAER ACKDPNPIID GRKANVNLAY LGAKPRSLQT GTRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : RBM38 RNA binding motif protein 38 [ Homo sapiens (human) ]
Official Symbol : RBM38
Synonyms : RNPC1; SEB4B; SEB4D; HSRNASEB; dJ800J21.2
Gene ID : 55544
mRNA Refseq : NM_183425
Protein Refseq : NP_906270
MIM : 612428
UniProt ID : Q9H0Z9

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