Recombinant Human RECK Protein, GST-tagged

• Cat.No.: RECK-550H
• Product Overview: Human RECK full-length ORF ( NP_066934.1, 1 a.a. - 971 a.a.) recombinant protein with GST-tag at N-terminal was expressed in vitro wheat germ expression system.

Specification

• Description: The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene.
• Source: Wheat germ
• Species: Human
• Tag: GST
• Molecular Mass: 132.9 kDa
• AA Sequence: MATVRASLRGALLLLLAVAGVAEVA GGLAPGSAGALCCNHSKDNQMCRDV CEQIFSSKSESRLKHLLQRAPDYCP ETMVEIWNCMNSSLPGVFKKSDGWV GLGCCELAIALECRQACKQASSKND ISKVCRKEYENALFSCISRNEMGSV CCSYAGHHTNCREYCQAIFRTDSSP GPSQIKAVENYCASISPQLIHCVNN YTQSYPMRNPTDSLYCCDRAEDHAC QNACKRILMSKKTEMEIVDGLIEGC KTQPLPQDPLWQCFLESSQSVHPGV TVHPPPSTGLDGAKLHCCSKANTST CRELCTKLYSMSWGNTQSWQEFDRF CEYNPVEVSMLTCLADVREPCQLGC RNLTYCTNFNNRPTELFRSCNAQSD QGAMNDMKLWEKGSIKMPFINIPVL DIKKCQPEMWKAIACSLQIKPCHSK SRGSIICKSDCVEILKKCGDQNKFP EDHTAESICELLSPTDDLKNCIPLD TYLRPSTLGNIVEEVTHPCNPNPCP ANELCEVNRKGCPSGDPCLPYFCVQ GCKLGEASDFIVRQGTLIQVPSSAG EVGCYKICSCGQSGLLENCMEMHCI DLQKSCIVGGKRKSHGTSFSIDCNV CSCFAGNLVCSTRLCLSEHSSEDDR RTFTGLPCNCADQFVPVCGQNGRTY PSACIARCVGLQDHQFEFGSCMSKD PCNPNPCQKNQRCIPKPQVCLTTFD KFGCSQYECVPRQLACDQVQDPVCD TDHMEHNNLCTLYQRGKSLSYKGPC QPFCRATEPVCGHNGETYSSVCAAY SDRVAVDYYGDCQAVGVLSEHSSVA ECASVKCPSLLAAGCKPIIPPGACC PLCAGMLRVLFDKEKLDTIAKVTNK KPITVLEILQKIRMHVSVPQCDVFG YFSIESEIVILIIPVDHYPKALQIE ACNKEAEKIESLINSDSPTLASHVP LSALIISQVQVSSSVPSAGVRARPS CHSLLLPLSLGLALHLLWTYN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: RECK reversion inducing cysteine rich protein with kazal motifs [ Homo sapiens (human) ]
• Official Symbol: RECK
• Synonyms: RECK; reversion inducing cysteine rich protein with kazal motifs
• Gene ID: 8434
• mRNA Refseq: NM_021111
• Protein Refseq: NP_066934
• MIM: 605227
• UniProt ID: O95980