Recombinant Human RECQL Protein (1-649 aa), His-tagged

• Cat.No.: RECQL-2818H
• Product Overview: Recombinant Human RECQL Protein (1-649 aa) is produced by Baculovirus expression system. This protein is fused with a 10xHis tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length.

Specification

• Description: DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.
• Source: Baculovirus
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 76.0 kDa
• Protein length: 1-649 aa
• AA Sequence: MASVSALTEELDSITSELHAVEIQI QELTERQQELIQKKKVLTKKIKQCL EDSDAGASNEYDSSPAAWNKEDFPW SGKVKDILQNVFKLEKFRPLQLETI NVTMAGKEVFLVMPTGGGKSLCYQL PALCSDGFTLVICPLISLMEDQLMV LKQLGISATMLNASSSKEHVKWVHA EMVNKNSELKLIYVTPEKIAKSKMF MSRLEKAYEARRFTRIAVDEVHCCS QWGHDFRPDYKALGILKRQFPNASL IGLTATATNHVLTDAQKILCIEKCF TFTASFNRPNLYYEVRQKPSNTEDF IEDIVKLINGRYKGQSGIIYCFSQK DSEQVTVSLQNLGIHAGAYHANLEP EDKTTVHRKWSANEIQVVVATVAFG MGIDKPDVRFVIHHSMSKSMENYYQ ESGRAGRDDMKADCILYYGFGDIFR ISSMVVMENVGQQKLYEMVSYCQNI SKCRRVLMAQHFDEVWNSEACNKMC DNCCKDSAFERKNITEYCRDLIKIL KQAEELNEKLTPLKLIDSWMGKGAA KLRVAGVVAPTLPREDLEKIIAHFL IQQYLKEDYSFTAYATISYLKIGPK ANLLNNEAHAITMQVTKSTQNSFRA ESSQTCHSEQGDKKMEEKNSGNFQK KAANMLQQSGSKNTGAKKRKIDDA
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: RECQL RecQ protein-like (DNA helicase Q1-like) [ Homo sapiens ]
• Official Symbol: RECQL
• Synonyms: RECQL; RecQ1; RecQL1; recQ protein-like 1; DNA-dependent ATPase Q1; DNA helicase, RecQ-like type 1; RECQL1
• Gene ID: 5965
• mRNA Refseq: NM_002907
• Protein Refseq: NP_002898
• MIM: 600537
• UniProt ID: P46063