Recombinant Human Regenerating Islet-derived 1 Alpha, His-tagged
Cat.No. : | REG1A-192H |
Product Overview : | Recombinant Human REG 1 alpha (His-tagged) contains 144 amino acids and has a molecular mass of 17.8 kDa. And this protein expressed inE.Coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | REG1A-192H |
Description : | REG protein was shown to be stimulated during the regeneration of pancreatic islets. Since then, many Reg-related proteins have been identified in humans and other animals. In human, the four REG family genes, i.e., REG 1 alpha, REG 1 beta, REG-related sequence (RS) and HIP/PAP, have so far been isolated. Reg protein is a growth factor for pancreatic beta cells and also suggest that the administration of Reg protein could be used as another therapeutic approach for diabetes mellitus. human REG cDNA which encoded a 166-amino acid protein with a 22-amino acid signal peptide. The amino acid sequence of human REG protein has 68% homology to that of rat Reg protein. Reg I was found to be expressed mainly in pancreatic beta and acinoductular cells as well as gastric fundic enterochromaffin-like (ECL) cells. |
Source : | E.Coli. |
Sequences of Amino Acids : | MKHHHHHHAS HMQEAQTELP QARISCPEGT NAYRSYCYYF NEDRETWVDA DLYCQNMNSG NLVSVLTQAE GAFVASLIKE SGTDDFNVWI GLHDPKKNRR WHWSSGSLVS YKSWGIGAPS SVNPGYCVSL TSSTGFQKWK DVPCEDKFSF VCKFKN. |
Specificity : | The amino acid sequence of the recombinant Human REG 1 alpha is 100% homologous to the amino acid sequence of the Human REG 1 alpha without signal sequence. |
Purification Method : | Two-step procedure using affinity Ni-NTA chromatography and size exclusion chromatography. |
Purity : | >95% (SDS-PAGE analyzed). |
Formulation : | Sterile filtered and lyophilized from 0.5 mg/ml in 5mM Tris, 25mM NaCl, pH 7.5. |
Reconstitution : | Add 0.2 ml of deionized H2O and let the lyophilized pellet dissolve completely. Storage: Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
Stability/Shelf Life : | The lyophilized protein remains stable until the expiry date when stored at -20°C. |
Applications : | Western blotting, ELISA. |
Gene Name : | REG1A regenerating islet-derived 1 alpha [ Homo sapiens ] |
Synonyms : | REG1A; REG; PSP; ICRF; MGC12447; P19; PSPS; PSPS1; PTP; MGC12447; protein-X; OTTHUMP00000160485; Islet cells regeneration factor; Islet of Langerhans regenerating protein; Pancreatic stone protein; Pancreatic thread protein; Regenerating protein I alpha; lithostathine 1 alpha; pancreatic stone protein, secretory; regenerating islet-derived 1 alpha; regenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic thread protein); Regenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic thread protein) |
Gene ID : | 5967 |
mRNA Refseq : | NM_002909 |
Protein Refseq : | NP_002900 |
MIM : | 167770 |
UniProt ID : | P05451 |
Chromosome Location : | 2p12 |
Function : | Binding; growth factor activity; sugar binding |
Products Types
◆ Recombinant Protein | ||
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REG1A-4646R | Recombinant Rat REG1A Protein, His (Fc)-Avi-tagged | +Inquiry |
REG1A-3661R | Recombinant Rhesus Macaque REG1A Protein, His (Fc)-Avi-tagged | +Inquiry |
REG1A-89C | Recombinant Cynomolgus REG1A protein(Met1-Asn166), His-tagged | +Inquiry |
REG1A-6163H | Recombinant Human REG1A Protein (Gln23-Asn166), C-His tagged | +Inquiry |
◆ Lysates | ||
REG1A-2497HCL | Recombinant Human REG1A cell lysate | +Inquiry |
REG1A-1364RCL | Recombinant Rat REG1A cell lysate | +Inquiry |
REG1A-988CCL | Recombinant Cynomolgus REG1A cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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