| Description : |
RELT, also known tumor necrosis factor receptor superfamily member 19L, is one of the the tumor necrosis factor receptor superfamily. It is expressed in hematopoietic tissues and peripheral blood leukocytes. This protein mediates activation of NF-kappa-B and plays a role in T-cell activation. With overexpression of this protein in HEK-293 cells, it induces p38 and JNK signaling and activates apoptosis. And it can also costimulate T-cell proliferation in the presence of CD3 signaling. Recombinant human RELT protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Source : |
Insect cell |
| Species : |
Human |
| Tag : |
hIgG-His |
| Form : |
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10 % glycerol. |
| Molecular Mass : |
41.4 kDa |
| Protein length : |
26-162 aa |
| AA Sequence : |
STTLWQCPPG EEPDLDPGQG TLCRPCPPGT FSAAWGSSPC QPHARCSLWR RLEAQVGMAT RDTLCGDCWP GWFGPWGVPR VPCQPCSWAPLGTHGCDEWG RRARRGVEVA AGASSGGETR QPGNGTRAGG PEETAAQVEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH |
| Endotoxin : |
< 1.0 EU per 1 ug of protein (determined by LAL method) |
| Purity : |
> 90 % by SDS - PAGE |
| Notes : |
For research use only. This product is not intended or approved for human, diagnostics or veterinary use. |
| Storage : |
Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : |
0.5 mg/ml (determined by Absorbance at 280 nm) |
