| Description : |
The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
39.3 kDa |
| AA Sequence : |
MPEGEDFGPGKSWEVINSKPDERPR LSHCIAESWMNFSIFLQEMSLFKQQ SPGKFCLLVCSVCTFFTILGSYIPG VILSYLLLLCAFLCPLFKCNDIGQK IYSKIKSVLLKLDFGIGEYINQKKR ERSEADKEKSHKDDSELDFSALCPK ISLTVAAKELSVSDTDVSEVSWTDN GTFNLSEGYTPQTDTSDDLDRPSEE VFSRDLSDFPSLENGMGTNDEDELS LGLPTELKRKKEQLDSGHRPSKETQ SAAGLTLPLNSDQTFHLMSNLAGDV ITAAVTAAIKDQLEGVQQALSQAAP IPEEDTDTEEGDDFELLDQSELDQI ESELGLTQDQEAEAQQNKKSSGFLS NLLGGHTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
