Recombinant Human REXO2 protein, His-tagged

• Cat.No.: REXO2-1941H
• Product Overview: Recombinant Human REXO2 aa. (Gln41~Asn213 (Accession # Q9Y3B8)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 21.7kDa
• Protein length: Gln41~Asn213 (Accession # Q9Y3B8)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% sarcosyl and 5% trehalose.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 5.7

Gene Information

• Gene Name: REXO2 RNA exonuclease 2 [ Homo sapiens (human) ]
• Official Symbol: REXO2
• Synonyms: REXO2; RNA exonuclease 2; RFN; SFN; REX2; CGI-114; oligoribonuclease, mitochondrial; REX2, RNA exonuclease 2 homolog; RNA exonuclease 2 homolog; small fragment nuclease
• Gene ID: 25996
• mRNA Refseq: NM_015523.3
• Protein Refseq: NP_056338.2
• UniProt ID: Q9Y3B8