Recombinant Human RGCC Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RGCC-4496H
• Product Overview: C13orf15 MS Standard C13 and N15-labeled recombinant protein (NP_054778) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 14.6 kDa
• AA Sequence: MKQPAAQGSPAAAAAAAPALDSAAA EDLSDALCEFDAVLADFASPFHERH FHYEEHLERMKRRSSASVSDSSGFS DSESADSLYRNSFSFSDEKLNSPTD STPALLSATVTPQKAKLGDTKELEA FIADLDKTLASMTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RGCC regulator of cell cycle [ Homo sapiens (human) ]
• Official Symbol: RGCC
• Synonyms: RGCC; regulator of cell cycle; RGC32; RGC-32; C13orf15; bA157L14.2; regulator of cell cycle RGCC; response gene to complement 32 protein
• Gene ID: 28984
• mRNA Refseq: NM_014059
• Protein Refseq: NP_054778
• MIM: 610077
• UniProt ID: Q9H4X1