Recombinant Human RHOD, His-tagged

• Cat.No.: RHOD-30391TH
• Product Overview: Recombinant fragment of Human RHOD with an N terminal His tag; 211 amino acids with the tag, predicted mwt: 23.8 kDa.

Specification

• Description: Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton.
• Protein length: 190 amino acids
• Conjugation: HIS
• Molecular Weight: 23.800kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 50% Glycerol, 5mM DTT, 200mM Sodium chloride, 20mM Tris HCl, 2mM EDTA, 0.1mM PMSF, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MMGSSHHHHHH SSGLVPRGSH MVKVVLVGDG GCGKTSLLMV FADGAFPESY TPTVFERYMV NLQVKGKPVH LHIWDTAGQD DYDRLRPLFY PDASVLLLCF DVTSPNSFDN IFNRWYPEVN HFCKKVPIIV VGCKTDLRKD KSLVNKLRRN GLEPVTYHRG QEMARSVGAV AYLECSARLH DNVHAVFQEA AEVALSSRGR NFWRRITQGF C
• Sequence Similarities: Belongs to the small GTPase superfamily. Rho family.

Gene Information

• Gene Name: RHOD ras homolog gene family, member D [ Homo sapiens ]
• Official Symbol: RHOD
• Synonyms: RHOD; ras homolog gene family, member D; ARHD; rho-related GTP-binding protein RhoD; Rho; Rho related GTP binding protein RhoD; Rho related protein HP1; RhoD; RhoHP1
• Gene ID: 29984
• mRNA Refseq: NM_014578
• Protein Refseq: NP_055393
• MIM: 605781
• Uniprot ID: O00212
• Chromosome Location: 11q14.3
• Pathway: Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding