Recombinant Human Ribosomal Protein L8, His-tagged RPL8-5549H

Recombinant Human Ribosomal Protein L8, His-tagged

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Recombinant Human Ribosomal Protein L8, His-tagged

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Cat.No. : RPL8-5549H Optional Service: Optional requirements on this protein
Product Overview : Recombinant humanRPL8 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by conventional chromatography, after refolding of the isolatedinclusion bodies in a renaturation buffer.
Description : RPL8 (60S ribosomal protein L8) belongs to the ribosomal protein L2Pfamily. Ribosomes, theorganelles that catalyze protein synthesis, consist of a small 40S subunitand a large 60S subunit. The protein belongs to the L2P family of ribosomalproteins. It is located in the cytoplasm and exists as a component of the 60S subunit where it isthought to play a role in aminoacyl-tRNA binding, specifically at theribosomal subunit interface.
Source : E. coli
Species : Human
Form : Liquid.In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 300mM NaCl,2mM EDTA.
Molecular Weight : 30.2kDa (277aa),confirmed by MALDI-TOF.
Purity : > 90%by SDS - PAGE.
Concentration : 0.25mg/ml (determinedby Bradford assay).
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAKVVFRDPYRFK KRTELFIAAE GIHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCLEEKP GDRGKLARASGNYATVISHN PETKKTRVKL PSGSKKVISS ANRAVVGVVA GGGRIDKPIL KAGRAYHKYK AKRNCWPRVRGVAMNPVEHP FGGGNHQHIG KPSTIRRDAP AGRKVGLIAA RRTGRLRGTK TVQEKEN
Storage : Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
OfficialSymbol : RPL8
Pathways : Cap-dependentTranslation Initiation; Cytoplasmic Ribosomal Proteins; DevelopmentalBiology; Diabetes pathways; Eukaryotic Translation Elongation; EukaryoticTranslation Initiation; Eukaryotic Translation Termination; Formation of apool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomalsubunit; Metabolism; Metabolism of mRNA; Nonsense Mediated Decay Independentof the Exon Junction Complex; Ribosome; TNF-alpha/NF-kB Signaling Pathway;Viral mRNA Translation
Gene Name : RPL8 ribosomal protein L8 [ Homosapiens ]
Synonyms : RPL8;ribosomal protein L8; L8; 60S ribosomal protein L8
Gene ID : 6132
mRNA Refseq : NM_000973
Protein Refseq : NP_000964
MIM : 604177
UniProt ID : P62917
Chromosome Location : 8q24.3
Function : RNA binding; rRNAbinding; structural constituent of ribosome
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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