Recombinant Human RIGI Protein, FLAG-Tagged

Species :	Human
Source :	HEK293
Tag :	Flag
Protein Length :	2-925(end)
Description :	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
Form :	Liquid
Molecular Mass :	108 kDa
Purity :	≥90%
Usage :	Research Use Only
Storage :	At least 6 months at –80°C.
Concentration :	0.73 mg/ml
Storage Buffer :	40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 100 µg/ml FLAG peptide, 20% glycerol, 3 mM DTT
Shipping :	-80°C
Warning :	Avoid freeze/thaw cycles.
Format :	Aqueous buffer solution.

Gene Name	RIGI RNA sensor RIG-I [ Homo sapiens (human) ]
Official Symbol	RIGI
Synonyms	DDX58, DDX58 Protein, DEAD box protein 58, retinoic acid inducible gene I, RIG-1, Antiviral innate immune response receptor RIG-I, Retinoic acid-inducible gene 1 protein, RIG1, RIGI, RIG-I, RIG-I-like receptor 1, RLR-1, SGMRT2
Gene ID	23586
mRNA Refseq	NM_014314.4
Protein Refseq	NP_055129.2
MIM	609631
UniProt ID	O95786